Cloudy
-1°CSun :Rain/Snow Showers. High: 4 Low: 1

Honey can help reverse bacterial resistance to antibiotics

Honey can help reverse bacterial resistance to antibiotics

Washington: A study has found that Manuka honey could help in clearing chronically infected wounds, and even in reversing bacterial resistance to antibiotics.

Professor Rose Cooper from the University of Wales Institute Cardiff is looking at how manuka honey interacts with three types of bacteria that commonly infest wounds: Pseudomonas aeruginosa, Group A Streptococci and Meticillin-resistant Staphylococcus aureus (MRSA).

Her group has found that honey can interfere with the growth of these bacteria in a variety of ways and suggests that honey is an attractive option for the treatment of drug-resistant wound infections.

Honey has long been acknowledged for its antimicrobial properties. Traditional remedies containing honey were used in the topical treatment of wounds by diverse ancient civilisations.

Manuka honey is derived from nectar collected by honeybees foraging on the manuka tree in New Zealand and is included in modern licensed wound-care products around the world.

However, the antimicrobial properties of honey have not been fully exploited by modern medicine, as its mechanisms of action are not yet known.

Cooper`s group is helping to solve this problem by investigating at a molecular level the ways in which manuka honey inhibits wound-infecting bacteria.

“Our findings with streptococci and pseudomonads suggest that manuka honey can hamper the attachment of bacteria to tissues which is an essential step in the initiation of acute infections,” she explained.

“Inhibiting attachment also blocks the formation of biofilms, which can protect bacteria from antibiotics and allow them to cause persistent infections.

“Other work in our lab has shown that honey can make MRSA more sensitive to antibiotics such as oxacillin – effectively reversing antibiotic resistance.

“This indicates that existing antibiotics may be more effective against drug-resistant infections if used in combination with manuka honey,” she revealed.

This research may increase the clinical use of manuka honey as doctors are faced with the threat of diminishingly effective antimicrobial options.

“We need innovative and effective ways of controlling wound infections that are unlikely to contribute to increased antimicrobial resistance. We have already demonstrated that manuka honey is not likely to select for honey-resistant bacteria,” Cooper said.

At present, most antimicrobial interventions for patients are with systemic antibiotics.

“The use of a topical agent to eradicate bacteria from wounds is potentially cheaper and may well improve antibiotic therapy in the future. This will help reduce the transmission of antibiotic-resistant bacteria from colonised wounds to susceptible patients,” she concluded.

The research was presented at the Society for General Microbiology`s Spring Conference in Harrogate.

 

Top Stories

Gautam_Gulatijpg_2_hvqpe

Bigg Boss 8: Gautam Gulati is the champ, say HT perusers

January-30-2015
Mainstream reality show Bigg Boss 8 is all situated for its excellent finale on January 31. Over the recent days, we saw
Microsoft_ap_2294854f

Microsoft dispatches new Outlook application for ios, Android clients

January-30-2015
Taking Gmail and other email applications head on, Microsoft has dispatched another Outlook application for ios and Android gadgets. The new application
vijender_2294869f

Harmed Vijender hauls out of National Games

January-30-2015
Star Indian boxer Vijender Singh has hauled out of the 35th National Games beginning tomorrow in the wake of neglecting to recuperate
modi_twitter-624x351

PM Modi’s locations e-Governance gathering on Twitter, pushes for versatile first methodology

January-30-2015
In a to start with, Prime Minister Narendra Modi today decided to deliver his comments to the eighteenth National Conference on e-Governance
ayushmann

Hawaizaada Review: Ayushmann stars in an illogical and exhausting film, flies around in batsuit

January-30-2015
Hawaizaada cases to be the story of Shivkar Talpade, a Maharasthrian researcher from the 1860s, who apparently manufactured the world’s initially unmanned
arvind-kejriwal

Get prepared to serve Delhi and make it ok for ladies: Arvind Kejriwal to AAP unit

January-30-2015
New Delhi: In an endeavor to activate the Aam Aadmi Party unit, AAP boss Arvind Kejriwal on Thursday spoke to his gathering