Partly Cloudy
4°CSun :Showers. High: 9 Low: 2

Wild almond tree oil `may help combat obesity and diabetes`

Wild almond tree oil `may help combat obesity and diabetes`

Washington: Researchers, including one of Indian origin, have found that a future weapon in the battle against obesity and diabetes could come in the form of an oil derived from the seeds of wild almond trees.

According to researchers at Missouri University of Science and Technology, the key to the oil’s potential lies in its ability to affect certain microorganisms living in our bellies.

In the study, the researchers reported that adding sterculic oil to the diets of obese laboratory mice increased their sensitivity to insulin. This was due to the oil’s effect on three types of microorganisms that live in the guts of the mice.

As a result, the researchers saw a “statistically significant improvement in glucose tolerance and insulin sensitivity in the obese mice,” Shreya Ghosh, a Ph.D. student in environmental engineering at Missouri S and T, said.

The sterculic oil had no adverse affects on lean mice fed the same diet.

Sterculic oil is extracted from the seeds of the wild almond tree known as Sterculia foetida.

The research by Ghosh and her advisor, Dr. Daniel Oerther, builds upon previous studies conducted at the University of Missouri-Columbia. In those studies, sterculic oil was found to suppress the bodily enzyme stearoyl-CoA desaturase 1 (SCD1).

SCD1 is associated with insulin resistance, a condition that can lead to diabetes and obesity.

Other studies have shown that obese mice deficient in the hormone leptin have a different composition of “gut microbiota” than do lean mice.

Leptin helps regulate metabolism, and a deficiency of the hormone can contribute to obesity, says Oerther, the John and Susan Mathes Chair of Environmental Engineering at Missouri S and T.

In the Missouri S and T study, a diet supplemented by sterculic oil also correlated with lower levels of three types of gut microbiota – Actinobacteria, Bacilli and Erysipelotrichia – in the obese mice.

It isn’t clear, however, whether the lower levels of those microbiota led to the improvement of glucose tolerance and insulin sensitivity among the obese mice, Oerther says.

To perform her experiments, Ghosh studied 28 male mice – 14 of them obese and 14 normal, and each of them five weeks old at the beginning of the study.

She separated the mice into four groups and for nine weeks, fed a standard diet to one group of obese mice and one group of non-obese mice.

Over the same period, she fed the same diet, supplemented with 0.5 percent of sterculic oil, to one group of obese mice and one group of non-obese mice. Ghosh recorded the weights, food consumption and glucose levels of the mice during the nine-week period.

After the nine weeks, researchers conducted a DNA analysis of the gut microbiota at King Abdullah Institute of Science and Technology in Saudi Arabia.

The results confirmed correlations between the diet, improved glucose tolerance and groups of microbes. Even though the mice fed a diet with sterculic oil did not experience weight loss, both Ghosh and Oerther believe their findings could lead to new insights into controlling diabetes and weight gain.

 

Top Stories

x26-1427364866-vikasswarup.jpg.pagespeed.ic.yW5f92qABg

Vikas Swarup, the Oscar winning ‘Slumdog Millionaire’ author selected as the new MEA representative

March-27-2015
Noted writer Vikas Swarup, who made his presentation with the success novel “Q&A” (on which Slumdog Millionaire was based) is the new
24244827

Now shop on Flipkart, Snapdeal on zero investment EMIs

March-27-2015
India’s eCommerce space is buzzing with new dispatches and key declarations in the most recent two days. On Tuesday, we heard how
KTM-Duke-200

Bajaj Pulsar RS200 Vs Hero Karizma ZMR and KTM Duke 200

March-27-2015
The most recent portion in Bajaj Auto’s tremendously anticipated arrangement Pulsar – RS200 – has been dispatched at Rs. 1.1 lakh (non-ABS
322166-arvind-kejriwal-prashant-bhushan-yogendra-yadav-sketch

AAP Crisis : Kumar Vishwas asks Bhushan and Yadav to quit nimbly

March-27-2015
Aam Aadmi Party (AAP) leader Kumar Vishwas on Friday approached senior gathering pioneers Prashant Bhushan and Yogendra Yadav to leave the gathering
A portrait of the Facebook logo in Ventura

Facebook talks up requirement for virtual reality, huge tech wagers

March-27-2015
Virtual reality, counterfeit consciousness and automatons will empower Facebook Inc to make a more similar and helpful informal community, the organization said
Jadeja-Dhoni-1-AFP1

India had a dazzling World Cup: If Times Now can’t see that, they don’t know cricket

March-27-2015
India might never again be one-day title holders yet MS Dhoni and his happy men in blue have issued us numerous motivations