The shady businessman Klaus Mandel (Christopher Waltz) spends time in Belgium prison for allegedly having set fire to a building in an insurance scam, that cost the live of an accountant. In order to get time off, Mandel offers to testify against his former partner and best friend Krieger (Matthias Redlhammer). Retired Cop Schimanski (Götz George), now living on a houseboat in Belgium, is asked to transport Mandel across the border to Germany and hand him over to the authorities there. Schimanski agrees reluctantly, but the pair – snobbish Mandel and proletarian Schimanski, who once attempted to book Mandel – make uneven travel-companions. The journey is interrupted when a pair of Romanian hit men tries to kill Mandel. Now tied together by handcuffs, Schimanski and Mandel have to find their way to safety via car, train or on foot.