God, depicted as a black woman in her kitchen, creates new life and experiments: Dr. Bardot, a brain surgeon overwhelmed by chaos; Esther, mourning her husband; and Lucia, a young girl seeking revenge. Her hands place them in a city, where a solar eclipse transports them to a tropical island. There, Santeria guardian angels guide them to a house by the ocean, where they are prepared for a healing ritual by black albinos, dwarfs, and nuns. The ritual, led by a Babalao, involves sacrifices. God observes the experiment from her kitchen window.