Left disfigured and without memory due to a car accident, the painter Andrea Spiegelman decides to retire with her husband to an isolated villa, the legacy of an eccentric uncle dedicated to the cultivation of psychoactive plants. With the help of a diary in which his uncle wrote down his experiences, Andrea begins to experiment with drugs extracted from plants. Thanks to drugs, the painter recovers the lost inspiration and returns to painting, but without realizing it, she is dragged into a whirlwind of hallucinations that lead her to no longer distinguish reality from fantasy...