Holy Week starts with two friends parting in the quest for relief from their respective pains. One seeks the girlfriend who abandoned him, while the other seeks to abandon everything. One travels the roads of Colombia in the company of two adolescents, discovering that their country is more than what the news portrays; the other, seeking a conclusion to his work, travels his inner self and explores the root of his pain. By the time their roads cross again, they will know that life is about the journey, not the destination.