Chiro Sakha Hey revolves around the story of Ishan (Mazumdar) and Tilottama (Tanushree). Ishan, who hails from an illustrious family, lost his father during his childhood. He then moved to North Bengal along with his paternal uncle Sibasish (Chanda, a lawyer, and mother Aloka (Mithu). Now he works as a professional photographer and is a skilled painter too. Tilottama, who lost her husband seven years ago, carries the trauma of some tragic incident from her past. Amidst acute despair, Tilotttama gets acquainted with Ishan, who brings a ray of hope to her life.