Gayford has started her career as production secretary on David Cronenberg's Dead Ringers (1988, starring Geneviève Bujold) and War of the Worlds (1988-90, starring Richard Chaves) and worked as assistant production coordinator on Camilla (1994) and as assistant production manager on the television drama Christmas in My Hometown (1996) and Johnny 2.0 (1997, with John Neville). Among her credits as production coordinator are the television thriller The Absolute Truth (1997, with Bruce Greenwood), I'll Be Home for Christmas (1997, with Jack Palance), the television drama Flood: A River's Rampage (1998, with Kate Vernon), the television drama My Father's Shadow: The Sam Sheppard Story (1998, with John Colicos), Deep in My Heart (1999, with Alice Krige), the thriller Judgment Day: The Ellie Nesler Story (1999), the television sport comedy Coming Unglued (1999, with Melanie Nicholls-King), Category 6: Day of Destruction (2004, with Brian Markinson, Glenn Morshower, Niel Wray and James Holt), The Big White (2005, with Robin Williams), the television drama Four Minutes (2005, with Christopher Plummer, music by John Frizzell, and executive produced by Gerald W. Abrams), Doomstown (2006), Daniel's Daughter (2008, produced by David Till and executive produced by Gerald W. Abrams), The National Tree (2009, also produced by Till and Abrams), and the television series The Wonderful World of Disney (1999), A Nero Wolfe Mystery (2001, with Bill Smitrovich and Saul Rubinek), Veritas: The Quest (2003), Runaway (2006, with Leslie Hope), Nikita (2010-13, starring Melinda Clarke), Beauty & the Beast (2013-15), and Heroes Reborn (2015, with Nazneen Contractor, Greg Grunberg, Cristine Rose, Eve Harlow and Raven Dauda).